The Research Assistant (GQD Sensitivity and Spectral Analysis) is responsible for working on Analyzing Sensitivity to Analytes, a key objective in evaluating graphene quantum dots (GQDs) as nanoscale sensors for blood-relevant analytes. This role will assist in conducting fluorescence quenching experiments, analyzing spectral data, and contributing to the development of response curves for various blood-relevant analytes, including dopamine, serotonin, oxytocin, and cortisol. This is an excellent opportunity to gain hands-on experience in spectroscopy, data analysis, and sensor development in a collaborative and multidisciplinary research environment. The position requires a commitment of 2+ hours per week.
1. Performs over 20 titration experiments per analyte using GQDs in aqueous suspension with varying concentrations of dopamine, serotonin, oxytocin, and cortisol, down to the nanomolar range.
2. Measures NIR fluorescence spectra of GQD suspensions before and after analyte addition using a spectrometer.
3. Generates sensor response curves for each analyte by analyzing spectral quenching data, including both linear and non-linear behaviors.
4. Quantifies the lowest detectable concentration for each analyte that can be distinguished from control samples within error bars.
5. Compares experimentally derived detection limits to blood-relevant analyte concentrations and assess GQD performance.
6. Identifies specific spectral features in GQD quenching that are characteristic of each analyte, contributing to their potential specificity in detection.
7. Organizes, processes, and analyzes experimental data, preparing it for integration into AI-based models in subsequent project objectives.
8. Maintains accurate and detailed laboratory records, including experimental protocols, results, and observations.
9. Participates in weekly lab meetings to present progress, troubleshoot experiments, and discuss results with the research team.
10. Performs other related duties as assigned.
• Currently enrolled in an undergraduate program in Chemistry, Biochemistry, Physics, Engineering, or a related field.
• Strong interest in spectroscopy, fluorescence imaging, and nanotechnology.
• Experience with fluorescence spectroscopy or working with optical equipment.
• Knowledge of basic statistical analysis for generating error bars and interpreting response curves.
• None
• None
• Knowledge of basic laboratory skills, including accurate pipetting, solution preparation, and data recording.
• Knowledge of basic data analysis tools such as Excel, Origin.
• Knowledge of presentation and training techniques.
• Knowledge of laboratory and research techniques and procedures.
• Knowledge of materials chemistry and microscopy
• Ability to perform research and document results.
• Ability to communicate effectively.
University Core Competencies definitions may be found on the Human Resources website and in the staff performance management system.
• Visual acuity to read information from computer screens, forms and other printed materials and information.
• Able to speak (enunciate) clearly in conversation and general communication.
• Hearing ability for verbal communication/conversation/responses via telephone, telephone systems, and face-to-face interactions.
• Manual dexterity for typing, writing, standing and reaching, flexibility, body movement for bending, crouching, walking, kneeling and prolonged sitting.
• Lifting and moving objects and equipment up to 10 lbs.
• Work is indoors and sedentary and is subject to schedule changes and/or variable work hours.
• This role is an on campus, in-person position.
• There are no harmful environmental conditions present for this job.
• The noise level in this work environment is usually moderate.
As an AA/EEO employer, TCU recruits, hires, and promotes qualified persons in all job classifications without regard to age, race, color, religion, sex, sexual orientation, gender, gender identity, gender expression, national origin, ethnic origin, disability, genetic information, covered veteran status, or any other basis protected by law.
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